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JANUS KINASE 2
Descriptors Found:
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DeCS
Descriptor
English
:
Janus Kinase 2
Descriptor
Spanish
:
Janus Quinasa 2
Descriptor
Portuguese
:
Janus Quinase 2
Tree Number:
D08.811.913.696.620.682.725.124.200
D12.776.476.393.200
D12.776.624.664.700.117
Definition
English
:
A Janus kinase subtype that is involved in signaling from
GROWTH HORMONE
RECEPTORS;
PROLACTIN
RECEPTORS; and a variety of CYTOKINE RECEPTORS such as
ERYTHROPOIETIN
RECEPTORS and INTERLEUKIN RECEPTORS. Dysregulation of
Janus kinase 2
due to GENETIC TRANSLOCATIONS have been associated with a variety of
MYELOPROLIFERATIVE DISORDERS.
History Note
English
:
2007(1992)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52254
Unique Identifier:
D053614
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS